I am having trouble with neuropathy as a result of my diabetes... I have peripheral neuropathy affecting both my hands and feet. My hands are such that I can no longer turn the pages in books--my fingers do not distinguish between the pages--so I have turned to reading from tablets, such as the various Kindles and Nooks. My most recent purchase was a 10" Lenovo Tablet made originally for AT&T. My eyesight is such that the 7" tablets no longer have a readable text on them for me... The ALA is reported to have a positive effect on the nerve loss in my legs.I no longer walk more than about 50 yards without getting into some degree of physical distress. And even when just walking around in my home, I tend to stagger much like a toddler does, for the same reason: I am having to learn how to walk again. My brain does not receive the proper signals from my feet, to tell it what I am doing.So, among other medications, I have added ALA to the mix. It is too early to tell if it is really working.