In a world where you have no idea what your digestive support supplement was cultured in, this is a great relief. To my knowledge, it does not contain any live bacterial culture additions. Which is OK because if given the proper enzymes, your small intestine & colon should be able to culture the exact amount of needed co-existing-bacteria. Contains all the digestive enzymes your system creates. I take one before each meal. Since using for four days, I have had less visits to the bathroom (for that special visit that is) stool is visibly more solid, & I feel that more energy & nutrients from my food is being absorbed. Since it appears to be reducing all bowel irritation, gas levels appear to be lower, which has made my tummy appear smaller & flatter. I highly recommend these. Will comment on immune system & long term benefits after a few months of using.